Tetrahydrofuran (THF) HPLC

Tetrahydrofuran (THF)

**Grade:** HyperSolv™ For HPLC

**Brand:** BDH (Bionova Reagents)

**Product Code:** 15247 SB

**CAS Number:** 109-99-9

**EC Number:** 203-726-8

**UN Number:** UN 2056

**Molecular Formula:** C₄H₈O

**Molecular Weight:** 72.11 g/mol

**Assay (GC):** ≥99.9%

**Appearance:** Clear, colourless liquid

**Pack Size:** 1 L

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## PRODUCT DESCRIPTION

HyperSolv™ Tetrahydrofuran (THF) is an ultra-high purity HPLC-grade solvent designed for chromatographic, spectroscopic and analytical laboratory applications. It provides excellent elution strength, low UV absorbance and minimal residue, making it ideal for high-sensitivity pharmaceutical, chemical and research analyses.

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## PHYSICAL & CHEMICAL PROPERTIES

| Property | Specification |
|———-|—————|
| Chemical Name | Tetrahydrofuran |
| Synonym | Oxolane |
| Molecular Formula | C₄H₈O |
| Molecular Weight | 72.11 g/mol |
| CAS Number | 109-99-9 |
| EC Number | 203-726-8 |
| Appearance | Clear, colourless liquid |
| Assay (GC) | ≥99.9% |
| Density (20°C) | 0.887–0.889 g/mL |
| Boiling Point | 65–67°C |
| Melting Point | −108°C |
| Flash Point | −17°C |
| Auto-ignition Temperature | ~321°C |
| Refractive Index (20°C) | 1.405–1.408 |

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## QUALITY SPECIFICATIONS

• HPLC Grade (HyperSolv™)

• Ultra-low UV absorbance

• Excellent chromatographic purity

• Low residue after evaporation

• High batch-to-batch consistency

• Suitable for gradient and isocratic HPLC

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## APPLICATIONS

• HPLC mobile phase preparation

• UHPLC analysis

• LC-MS applications

• Organic synthesis

• Polymer chemistry

• Pharmaceutical quality control

• Chemical research laboratories

• Extraction procedures

• Cleaning of analytical equipment

• Spectroscopic analysis

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## STORAGE CONDITIONS

• Store tightly closed in a cool, dry and well-ventilated area.

• Protect from heat, sparks and open flames.

• Store below 25°C.

• Keep away from oxidizing agents.

• Keep container tightly sealed to minimize peroxide formation.

• Store under recommended laboratory chemical storage conditions.

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## SAFETY INFORMATION

**GHS Classification**

• Highly Flammable Liquid (Category 2)

• Acute Toxicity (Category 4)

• Eye Irritation (Category 2)

• Specific Target Organ Toxicity – Single Exposure (Category 3)

**Signal Word:** Danger

**Hazard Statements**

• Highly flammable liquid and vapour.

• Harmful if swallowed or inhaled.

• Causes serious eye irritation.

• May cause drowsiness or dizziness.

• May form explosive peroxides during prolonged storage.

**Recommended PPE**

• Chemical-resistant gloves

• Laboratory coat

• Safety goggles or face shield

• Appropriate respirator where ventilation is inadequate

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## PACKAGING

• Amber chemical-resistant bottle

• Chemical-resistant screw cap

• Leak-proof laboratory packaging

• Suitable for transport of flammable solvents

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## SHELF LIFE

Refer to the manufacturer’s expiry date. Product should be inspected periodically for peroxide formation after prolonged storage or repeated opening.

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## WLS QUALITY INSIGHT

HyperSolv™ HPLC Grade Tetrahydrofuran is a premium analytical solvent suitable for demanding chromatographic applications requiring exceptional purity and reproducibility. Due to its tendency to form explosive peroxides during storage, laboratories should follow recommended storage practices and test aged containers before distillation or concentration. This product is ideal for pharmaceutical, research, petrochemical and analytical laboratories requiring reliable HPLC performance.