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ATROPINE SULPHATE MONOHYDRATE
Atropine Standard
Alkaloids
ATROPINE SULPHATE MONOHYDRATE (5 g)
Product Name: Atropine Sulphate Monohydrate
CAS No.: 5908-99-6
Molecular Formula: (C₁₇H₂₃NO₃)₂·H₂SO₄·H₂O
Molecular Weight: 694.83 g/mol
Description
Pharmaceutical and analytical-grade atropine salt (tropane alkaloid derivative), widely used as a biochemical reagent and reference compound in laboratory and pharmaceutical applications.
Specifications (Benchmark: Sigma-Aldrich / Merck / Loba / Fisher)
Assay (Purity): ≥ 98.0 – 99.5%
Grade: AR / ACS / Pharmaceutical / Reagent grade
Form: Crystalline powder
Appearance: White to off-white solid
pH (1% solution): ~5.0 – 6.5
Loss on Drying: ≤ 1.0%
Key Properties
Solubility: Freely soluble in water and ethanol
Stability: Stable under recommended conditions; light-sensitive
Melting Range: ~190–200°C (decomposes)
Applications
Analytical reagent in biochemical and pharmacological studies – ALKALOIDS
Standard/reference material in pharmaceutical labs
Anticholinergic research applications
Used in formulation and assay development
Hazard Information (GHS)
Classification: Acute toxicity, harmful if swallowed/inhaled
Hazards: Neurotoxic alkaloid; may cause serious systemic effects
Precautions: Avoid exposure; use full PPE (gloves, goggles, respirator where needed)
Handling
Handle strictly in controlled laboratory conditions
Avoid dust formation and inhalation
Use fume hood for weighing/transfer
Storage
Store in cool (15–25°C), dry, well-ventilated area
Keep tightly closed in amber container (light protection)
Keep away from oxidizing agents
Packaging
Pack Size: 5 g
Container: Amber glass reagent bottle with tamper-proof cap
Supplier Benchmarks / Equivalents
Sigma-Aldrich: Atropine sulfate monohydrate ≥99%
Merck (Millipore): Analytical/Pharma grade
Fisher Scientific: Certified reagent grade
Loba Chemie: Extra Pure / AR grade (as shown)
Molychem / BDH / J.T. Baker: Equivalent lab-grade offerings
Safety Note
Strictly for laboratory/professional use only.
Highly bioactive compound — misuse can be hazardous.
Always follow SDS/MSDS and institutional safety protocols.
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